Welcome to CancerSEA-X, a single-cell resource dedicated to TME cell states

Introduction

CancerSEA-X is a comprehensive cancer single-cell state resource, systematically characterizing 156 distinct cell states across malignant, immune, and stromal cells. By analyzing 239 scRNA-seq datasets covering 32 cancer types, it provides a pan-cancer tumor microenvironment(TME) cell state atlas.

Features

  1. 1. TME Cell State Exploration
    • Covers 25 cancer cell states, 105 immune cell states, and 26 stromal cell states
    • Enables one-stop query and download of signature genes and functional activity spectrum for cell states
  2. 2. Bidirectional State-Gene Search
    • Select a cell state: Obtain a list of genes significantly correlated with the state in a specific cancer type
    • Input a gene: Retrieve significantly correlated cell states in a specific cancer type and detailed correlation information
  3. 3. Cross-cell-type State-Gene Network
    • Visualize functional associations between cell states and genes
    • Supports interactive exploration of key cell state(s) and gene(s)

Statistics

156
Cell states
32
Cancer types
239
Datasets
9,608,163
Single cells
25
Cancer cell states
52
T cell states
19
B cell states
3
Monocyte states
16
Macrophage states
15
Dendritic cell states
12
CAF states
14
Endothelial cell states

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