Welcome to SEECancer database

Click evolutionary stage to quick search early late relapse metastasis drug resistant drug induced

Introduction for SEECancer

Cancer is driven by accumulating somatic alterations which confer normal cells fitness advantage to evolve from a premalignant status to malignant tumor. The SEECancer database presents the comprehensive cancer evolutionary stage-specific somatic events (including early-specific, late-specific, relapse-specific, metastasis-specific, drug-resistant and drug-induced genomic events) and their temporal orders.

Overview of SEECancer

All records in SEECancer are manually verified. Through processing more than 10,000 published articles, the current version of SEECancer contains 1231 evolutionary stage-specific genomic events and 5772 temporal orders between different types of somatic changes across 82 human cancers, referring to 23 tissue origins.

What can users do in SEECancer

-browse all kinds of genomic events occurring in different stages of cancer evolution;
-search evolutionary stage-specific somatic events by key words;
-search the temporal orders related to a particular gene in a selected cancer;
-download the evolutionary stage-specific somatic events and their temporal sequence data;

Cite

If you use SEECancer in your work, please cite our publication:
SEECancer: a resource for somatic events in evolution of cancer genome. Nucleic Acids Research. 2018.